Mymk - myomaker, myoblast fusion factor Gene

Also Known as Tmem8c; myomaker; 1110002H13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66139

Summary

Involved in myoblast fusion; plasma membrane fusion; and positive regulation of skeletal muscle hypertrophy. Acts upstream of or within myoblast fusion involved in skeletal muscle regeneration. Located in plasma membrane. Is integral component of Golgi membrane and integral component of plasma membrane. Is expressed in several structures, including limb; skeletal musculature; somite; and tongue. Human ortholog(s) of this gene implicated in Carey-Fineman-Ziter syndrome. Orthologous to human MYMK (myomaker, myoblast fusion factor). [provided by Alliance of Genome Resources, Apr 2022]

Mymk Products (2)

mRNA Protein Name
NM_001159602.1 NP_001153074.1 protein myomaker isoform 2
NM_025376.3 NP_079652.1 protein myomaker isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28386024 MGI
Biological Process GO Annotation Evidence References Source
involved in myoblast fusion IDA
IDA: Inferred from direct assay
23868259 MGI
acts upstream of or within myoblast fusion involved in skeletal muscle regeneration IMP
IMP: Inferred from mutant phenotype
25085416 MGI
involved in plasma membrane fusion IDA
IDA: Inferred from direct assay
23868259 MGI
involved in positive regulation of skeletal muscle hypertrophy IDA
IDA: Inferred from direct assay
28186492 MGI
acts upstream of or within skeletal muscle tissue regeneration IMP
IMP: Inferred from mutant phenotype
25085416 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
28860190 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
23868259 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein myomaker

  • myoblast fusion maker

  • transmembrane protein 8C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08927 MYMK Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mymk NCBI NCBI:389827