Atp6v1g2 - ATPase, H+ transporting, lysosomal V1 subunit G2 Gene

Also Known as NG38; VAG2; Atp6g2; 1500002D01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66237

Summary

Enables ATP hydrolysis activity and proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to act upstream of or within ion transport. Is integral component of synaptic vesicle membrane. Part of vacuolar proton-transporting V-type ATPase complex. Is expressed in several structures, including nervous system. Orthologous to human ATP6V1G2 (ATPase H+ transporting V1 subunit G2). [provided by Alliance of Genome Resources, Apr 2022]

Atp6v1g2 Products (2)

mRNA Protein Name
NM_001347351.1 NP_001334280.1 V-type proton ATPase subunit G 2 isoform 2
NM_023179.3 NP_075668.1 V-type proton ATPase subunit G 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP hydrolysis activity IDA
IDA: Inferred from direct assay
12133826 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12133826 MGI
enables proton-transporting ATPase activity, rotational mechanism IDA
IDA: Inferred from direct assay
12527205 MGI
Biological Process GO Annotation Evidence References Source
involved in synaptic vesicle lumen acidification EXP
EXP: Inferred from Experiment
28793259 MGI
involved in synaptic vesicle lumen acidification IDA
IDA: Inferred from direct assay
28793259 MGI
involved in synaptic vesicle lumen acidification IMP
IMP: Inferred from mutant phenotype
28793259 MGI
Cellular Component GO Annotation Evidence References Source
located in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
12133826 MGI
part of vacuolar proton-transporting V-type ATPase complex IPI
IPI: Inferred from physical interaction
12133826 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

V-type proton ATPase subunit G 2

  • ATPase, H+ transporting, V1 subunit G

  • ATPase, H+ transporting, lysosomal (vacuolar proton pump)

  • ATPase, H+ transporting, lysosomal 13kD, V1 subunit G

  • V-ATPase 13 kDa subunit 2

  • V-ATPase subunit G 2

  • lysosomal 13kDa

  • vacuolar proton pump subunit G 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01232 ATP6V1G2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp6v1g2 NCBI NCBI:534