Atp6v1g1 - ATPase, H+ transporting, lysosomal V1 subunit G1 Gene

Mus musculus

Also known as VAG1; ATP6J; Vma10; Atp6g1; 1810024D14Rik

Gene ID: 66290 | Gene type: protein coding

About Atp6v1g1

Summary

Enables ATP hydrolysis activity and proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in cellular iron ion homeostasis and cellular response to increased oxygen levels. Predicted to act upstream of or within ion transport. Located in cytosol; lysosomal membrane; and plasma membrane. Part of vacuolar proton-transporting V-type ATPase complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human ATP6V1G1 (ATPase H+ transporting V1 subunit G1). [provided by Alliance of Genome Resources, Apr 2022]

Atp6v1g1 Products(1)

mRNA	Protein	Name
NM_024173.2	NP_077135.1	V-type proton ATPase subunit G 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables ATP hydrolysis activity	IDA IDA: Inferred from direct assay	12133826	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	12133826	MGI
enables proton-transporting ATPase activity, rotational mechanism	IDA IDA: Inferred from direct assay	12527205	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in synaptic vesicle lumen acidification	EXP EXP: Inferred from Experiment	28793259	MGI
involved in synaptic vesicle lumen acidification	IDA IDA: Inferred from direct assay	28793259	MGI
involved in synaptic vesicle lumen acidification	IMP IMP: Inferred from mutant phenotype	28793259	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of ATPase complex	IDA IDA: Inferred from direct assay	12527205	MGI
located in cytosol	IDA IDA: Inferred from direct assay	16177003	MGI
located in intracellular anatomical structure	IDA IDA: Inferred from direct assay	12133826	MGI
located in lysosomal membrane	IDA IDA: Inferred from direct assay	12133826	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	16177003	MGI
part of proton-transporting V-type ATPase complex	IDA IDA: Inferred from direct assay	12527205	MGI
part of proton-transporting V-type ATPase, V1 domain	IDA IDA: Inferred from direct assay	12527205	MGI
NOT located in synaptic vesicle	IDA IDA: Inferred from direct assay	12133826	MGI
part of vacuolar proton-transporting V-type ATPase complex	IPI IPI: Inferred from physical interaction	12133826	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

V-type proton ATPase subunit G 1

ATPase, H+ transporting, V1 subunit G	ATPase, H+ transporting, lysosomal (vacuolar proton pump)
ATPase, H+ transporting, lysosomal 13kD, V1 subunit G	V-ATPase 13 kDa subunit 1
V-ATPase subunit G 1	lysosomal 13kDa
vacuolar proton pump subunit G 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01231	ATP6V1G1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Atp6v1g1	NCBI	NCBI:9550

Name
Email *

	Sorry, but the email address you supplied was invalid.