2. Gene
  3. Sar1b - secretion associated Ras related GTPase 1B Gene

Sar1b - secretion associated Ras related GTPase 1B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CMRD; Sarb; Sara2; Sara1b; 2310075M17Rik; 2900019I22Rik

Gene ID: 66397 | Gene type: protein coding

About Sar1b

Summary

Predicted to enable GTPase activity. Predicted to be involved in several processes, including endoplasmic reticulum to Golgi vesicle-mediated transport; intracellular protein transport; and regulation of intracellular transport. Predicted to act upstream of or within protein transport and vesicle-mediated transport. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Human ortholog(s) of this gene implicated in chylomicron retention disease. Orthologous to human SAR1B (secretion associated Ras related GTPase 1B). [provided by Alliance of Genome Resources, Apr 2022]

Sar1b Products(1)

mRNA Protein Name
NM_025535.2 NP_079811.1 GTP-binding protein SAR1b
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11422940 MGI
Biological Process GO Annotation Evidence Reference Source
involved in lipid export from cell IMP
IMP: Inferred from mutant phenotype
33186557 MGI
involved in lipoprotein transport IMP
IMP: Inferred from mutant phenotype
33186557 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GTP-binding protein SAR1b

SAR1 gene homolog B

SAR1a gene homolog 2

SAR1b gene homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12443 SAR1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sar1b NCBI NCBI:51128