Drap1 - Dr1 associated protein 1 (negative cofactor 2 alpha) Gene

Also Known as NC2-alpha; 2310074H19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66556

Summary

Enables transcription corepressor activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including early conceptus; genitourinary system; and limb. Orthologous to human DRAP1 (DR1 associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Drap1 Products (2)

mRNA Protein Name
NM_001291080.1 NP_001278009.1 dr1-associated corepressor isoform 1
NM_024176.2 NP_077138.1 dr1-associated corepressor isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12471260 MGI
enables transcription corepressor activity IDA
IDA: Inferred from direct assay
12471260 MGI
enables transcription factor binding IDA
IDA: Inferred from direct assay
12471260 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12471260 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
12471260 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dr1-associated corepressor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03989 DRAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Drap1 NCBI NCBI:10589