Drap1 - Dr1 associated protein 1 (negative cofactor 2 alpha) Gene

Mus musculus

Also known as NC2-alpha; 2310074H19Rik

Gene ID: 66556 | Gene type: protein coding

About Drap1

Summary

Enables transcription corepressor activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including early conceptus; genitourinary system; and limb. Orthologous to human DRAP1 (DR1 associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Drap1 Products(2)

mRNA	Protein	Name
NM_001291080.1	NP_001278009.1	dr1-associated corepressor isoform 1
NM_024176.2	NP_077138.1	dr1-associated corepressor isoform 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	12471260	MGI
enables transcription corepressor activity	IDA IDA: Inferred from direct assay	12471260	MGI
enables transcription factor binding	IDA IDA: Inferred from direct assay	12471260	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	12471260	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	12471260	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dr1-associated corepressor

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03989	DRAP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Drap1	NCBI	NCBI:10589

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