2. Gene
  3. Exosc1 - exosome component 1 Gene

Exosc1 - exosome component 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2610035C18Rik; 2610104C07Rik; 2610312F07Rik

Gene ID: 66583 | Gene type: protein coding

About Exosc1

Summary

Predicted to enable RNA binding activity. Predicted to act upstream of or within RNA processing. Predicted to be located in nucleolus. Predicted to be part of nuclear exosome (RNase complex). Predicted to be active in cytoplasm. Is expressed in embryo and submandibular gland primordium. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human EXOSC1 (exosome component 1). [provided by Alliance of Genome Resources, Apr 2022]

Exosc1 Products(5)

mRNA Protein Name
NM_001164561.1 NP_001158033.1 exosome complex component CSL4 isoform 2
NM_001320231.1 NP_001307160.1 exosome complex component CSL4 isoform 3
NM_001320232.1 NP_001307161.1 exosome complex component CSL4 isoform 4
NM_001320233.1 NP_001307162.1 exosome complex component CSL4 isoform 5
NM_025644.4 NP_079920.1 exosome complex component CSL4 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21791617 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

exosome complex component CSL4

3'-5' exoribonuclease CSL4 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04596 EXOSC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Exosc1 NCBI NCBI:51013