Stoml2 - stomatin (Epb7.2)-like 2 Gene

Mus musculus

Also known as MSLP2; SLP-2; 0610038F01Rik

Gene ID: 66592 | Gene type: protein coding

About Stoml2

Summary

Predicted to enable GTPase binding activity and cardiolipin binding activity. Involved in several processes, including mitochondrial ATP synthesis coupled proton transport; positive regulation of interleukin-2 production; and stress-induced mitochondrial fusion. Located in mitochondrion. Is extrinsic component of plasma membrane. Orthologous to human STOML2 (stomatin like 2). [provided by Alliance of Genome Resources, Apr 2022]

Stoml2 Products(1)

mRNA	Protein	Name
NM_023231.2	NP_075720.1	stomatin-like protein 2, mitochondrial

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in CD4-positive, alpha-beta T cell activation	IMP IMP: Inferred from mutant phenotype	23028053	MGI
involved in lipid localization	IMP IMP: Inferred from mutant phenotype	23028053	MGI
involved in mitochondrial protein processing	IMP IMP: Inferred from mutant phenotype	19360003	MGI
NOT involved in mitochondrion localization	IMP IMP: Inferred from mutant phenotype	22623988	MGI
involved in positive regulation of interleukin-2 production	IMP IMP: Inferred from mutant phenotype	23028053	MGI
involved in proton motive force-driven mitochondrial ATP synthesis	IMP IMP: Inferred from mutant phenotype	23028053	MGI
involved in stress-induced mitochondrial fusion	IMP IMP: Inferred from mutant phenotype	19360003	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrion	IDA IDA: Inferred from direct assay	22623988	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	22623988	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

stomatin-like protein 2, mitochondrial

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-122671	OB-1	Inhibitor	99.40%	Unkown
HY-RS13950	STOML2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-122671S	OB-1-d3	Control	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Stoml2	NCBI	NCBI:30968

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