Zbed6 - zinc finger, BED type containing 6 Gene

Also Known as MGR; Gm8466; Gm38394

Species: Mus musculus

Gene Type: protein coding
Gene ID: 667118

Summary

Enables transcription cis-regulatory region binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; regulation of Insulin secretion involved in cellular response to glucose stimulus; and type B pancreatic cell differentiation. Acts upstream of or within blastocyst hatching. Located in cytoplasm and nucleolus. Is expressed in early conceptus; nervous system; neural retina; and secondary oocyte. Orthologous to human ZBED6 (zinc finger BED-type containing 6). [provided by Alliance of Genome Resources, Apr 2022]

Zbed6 Products (2)

mRNA Protein Name
NM_001166552.2 NP_001160024.1 zinc finger BED domain-containing protein 6
NM_001395904.1 NP_001382833.1 zinc finger BED domain-containing protein 6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
20016685 MGI
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
20016685 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within blastocyst hatching IMP
IMP: Inferred from mutant phenotype
27869233 MGI
involved in negative regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
20016685 MGI
involved in negative regulation of muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
32557799 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
20134481 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
20016685 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
29440408 MGI
involved in regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
29440408 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
24043816 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
20016685 MGI
located in nucleus IDA
IDA: Inferred from direct assay
20016685 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger BED domain-containing protein 6

  • muscle growth regulator

  • zinc finger, BED domain containing 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15957 ZBED6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zbed6 NCBI NCBI:100381270