Efcab1 - EF-hand calcium binding domain 1 Gene

Also Known as Clxn; 4930449A16Rik; 5430404L10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66793

Summary

Predicted to enable several functions, including beta-tubulin binding activity; calcium-dependent outer dynein arm binding activity; and dynein heavy chain binding activity. Predicted to act upstream of or within cell chemotaxis; cilium-dependent cell motility; and regulation of flagellated sperm motility. Predicted to be located in 9+2 motile cilium and axoneme. Is expressed in central nervous system and pancreas trunk epithelium. Orthologous to human EFCAB1 (EF-hand calcium binding domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Efcab1 Products (1)

mRNA Protein Name
NM_025769.3 NP_080045.1 calaxin

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of cilium movement IMP
IMP: Inferred from mutant phenotype
31240264 MGI
involved in regulation of flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
31240264 MGI
Cellular Component GO Annotation Evidence References Source
located in cilium IDA
IDA: Inferred from direct assay
31240264 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calaxin

EF-hand calcium-binding domain-containing protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02851 CLXN Human Pre-designed siRNA Set A Pre-designed Set / Unkown