Plin5 - perilipin 5 Gene

Also Known as MLDP; Lsdp5; PAT-1; 2310076L09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66968

Summary

Enables identical protein binding activity and Lipase binding activity. Involved in several processes, including negative regulation of peroxisome proliferator activated receptor signaling pathway; positive regulation of sequestering of triglyceride; and regulation of lipid metabolic process. Located in cytosol and lipid droplet. Orthologous to human PLIN5 (perilipin 5). [provided by Alliance of Genome Resources, Apr 2022]

Plin5 Products (2)

mRNA Protein Name
NM_001077348.1 NP_001070816.1 perilipin-5
NM_025874.3 NP_080150.2 perilipin-5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
21148142 MGI
enables lipase binding IPI
IPI: Inferred from physical interaction
19717842 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21148142 MGI
Biological Process GO Annotation Evidence References Source
involved in lipid droplet organization IMP
IMP: Inferred from mutant phenotype
22532565 MGI
involved in lipid storage IDA
IDA: Inferred from direct assay
22675471 MGI
involved in lipid storage IMP
IMP: Inferred from mutant phenotype
21148142 MGI
involved in mitochondrion localization IMP
IMP: Inferred from mutant phenotype
21885430 MGI
involved in negative regulation of fatty acid beta-oxidation IDA
IDA: Inferred from direct assay
21885430 MGI
involved in negative regulation of fatty acid beta-oxidation IMP
IMP: Inferred from mutant phenotype
22532565 MGI
involved in negative regulation of lipase activity IMP
IMP: Inferred from mutant phenotype
22532565 MGI
involved in negative regulation of lipid catabolic process IDA
IDA: Inferred from direct assay
21885430 MGI
involved in negative regulation of peroxisome proliferator activated receptor signaling pathway IDA
IDA: Inferred from direct assay
22675471 MGI
involved in negative regulation of reactive oxygen species metabolic process IMP
IMP: Inferred from mutant phenotype
22532565 MGI
involved in negative regulation of triglyceride catabolic process IDA
IDA: Inferred from direct assay
22675471 MGI
involved in positive regulation of fatty acid beta-oxidation IDA
IDA: Inferred from direct assay
17130488 MGI
involved in positive regulation of sequestering of triglyceride IDA
IDA: Inferred from direct assay
22675471 MGI
involved in positive regulation of triglyceride biosynthetic process IDA
IDA: Inferred from direct assay
17130488 MGI
involved in positive regulation of triglyceride biosynthetic process IMP
IMP: Inferred from mutant phenotype
22532565 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19717842 MGI
located in cytosol IDA
IDA: Inferred from direct assay
16571721 MGI
colocalizes with lipid droplet IDA
IDA: Inferred from direct assay
17130488 MGI
located in lipid droplet IDA
IDA: Inferred from direct assay
16571721 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

perilipin-5

  • lipid droplet associated protein

  • lipid droplet-associated protein PAT-1

  • lipid storage droplet protein 5

  • myocardial LD protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-111952 SR-4995 98.26% Unkown
HY-111953 SR-4559 98.81% Unkown
HY-RS10710 PLIN5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plin5 NCBI NCBI:440503