Upf3a - UPF3 regulator of nonsense transcripts homolog A (yeast) Gene

Also Known as UPF3; RENT3A; 2600001C03Rik; 4930546M19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67031

Summary

Predicted to enable mRNA binding activity and telomeric DNA binding activity. Predicted to be involved in positive regulation of translation. Predicted to act upstream of or within response to unfolded protein. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of exon-exon junction complex. Predicted to be active in cytoplasm and nucleolus. Is expressed in central nervous system. Orthologous to human UPF3A (UPF3A regulator of nonsense mediated mRNA decay). [provided by Alliance of Genome Resources, Apr 2022]

Upf3a Products (1)

mRNA Protein Name
NM_025924.2 NP_080200.1 regulator of nonsense transcripts 3A

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of in utero embryonic development IMP
IMP: Inferred from mutant phenotype
27040500 MGI
involved in negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IGI
IGI: Inferred from genetic interaction
27040500 MGI
involved in negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IMP
IMP: Inferred from mutant phenotype
27040500 MGI
acts upstream of or within positive regulation of mRNA cis splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
16789828 MGI
acts upstream of spermatogenesis IMP
IMP: Inferred from mutant phenotype
27040500 MGI
Cellular Component GO Annotation Evidence References Source
located in neuron projection IDA
IDA: Inferred from direct assay
23821644 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

regulator of nonsense transcripts 3A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15484 UPF3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Upf3a NCBI NCBI:65110