Mmachc - methylmalonic aciduria cblC type, with homocystinuria Gene

Mus musculus

Also known as CblC; 1810037K07Rik

Gene ID: 67096 | Gene type: protein coding

About Mmachc

Summary

Predicted to enable several functions, including anion binding activity; cyanocobalamin reductase (cyanide-eliminating) activity; and protein homodimerization activity. Predicted to be involved in cobalamin metabolic process; demethylation; and glutathione metabolic process. Located in mitochondrion. Is expressed in several structures, including embryo ectoderm; gut; heart; lung; and mesonephros mesenchyme. Used to study methylmalonic aciduria and homocystinuria type cblC. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblC. Orthologous to human MMACHC (metabolism of cobalamin associated C). [provided by Alliance of Genome Resources, Apr 2022]

Mmachc Products(1)

mRNA	Protein	Name
NM_025962.3	NP_080238.2	cyanocobalamin reductase / alkylcobalamin dealkylase

Protein Preferred Names

Protein Names

cyanocobalamin reductase / alkylcobalamin dealkylase

alkylcobalamin:glutathione S-alkyltransferase	cyanocobalamin reductase (cyanide-eliminating)
methylmalonic aciduria and homocystinuria type C protein homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS29477	Mmachc Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08509	MMACHC Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mmachc	NCBI	NCBI:25974

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