2. Gene
  3. Pagr1a - PAXIP1 associated glutamate rich protein 1A Gene

Pagr1a - PAXIP1 associated glutamate rich protein 1A Gene

  • Gene
  • Protein
  • Agent
Mus musculus

Also known as PA1; PAGR1; 2900092E17Rik

Gene ID: 67278 | Gene type: protein coding

About Pagr1a

Summary

Predicted to enable Estrogen receptor binding activity. Involved in positive regulation of isotype switching to IgG isotypes; positive regulation of response to DNA damage stimulus; and regulation of cell cycle G2/M phase transition. Acts upstream of or within chorion development and histone H3-K27 demethylation. Part of Histone Methyltransferase complex. Is expressed in several structures, including extraembryonic component. Orthologous to human PAGR1 (PAXIP1 associated glutamate rich protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pagr1a Products(1)

mRNA Protein Name
NM_030240.1 NP_084516.1 PAXIP1-associated glutamate-rich protein 1A
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
22949634 MGI
Biological Process GO Annotation Evidence Reference Source
involved in DNA damage response IMP
IMP: Inferred from mutant phenotype
19124460 MGI
acts upstream of or within chorion development IMP
IMP: Inferred from mutant phenotype
24633704 MGI
involved in positive regulation of isotype switching to IgG isotypes IMP
IMP: Inferred from mutant phenotype
26744420 MGI
involved in regulation of cell cycle G2/M phase transition IMP
IMP: Inferred from mutant phenotype
19124460 MGI
Cellular Component GO Annotation Evidence Reference Source
part of histone methyltransferase complex IDA
IDA: Inferred from direct assay
22949634 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PAXIP1-associated glutamate-rich protein 1A

PAXIP1-associated glutamate-rich protein 1

PAXIP1-associated protein 1

PTIP-associated 1

PTIP-associated protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09978 PAGR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown