2. Gene
  3. Slc25a19 - solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 Gene

Slc25a19 - solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as DNC; TPC; MUP1; 2900089E13Rik

Gene ID: 67283 | Gene type: protein coding

About Slc25a19

Summary

Predicted to enable thiamine transmembrane transporter activity. Predicted to be involved in thiamine pyrophosphate transmembrane transport. Located in mitochondrion. Is expressed in central nervous system; embryo; retina inner nuclear layer; retina layer; and retina outer nuclear layer. Human ortholog(s) of this gene implicated in inherited metabolic disorder and microcephaly. Orthologous to human SLC25A19 (solute carrier family 25 member 19). [provided by Alliance of Genome Resources, Apr 2022]

Slc25a19 Products(5)

mRNA Protein Name
NM_001252384.1 NP_001239313.1 mitochondrial thiamine pyrophosphate carrier isoform 1
NM_001252394.1 NP_001239323.1 mitochondrial thiamine pyrophosphate carrier isoform 2
NM_001252395.1 NP_001239324.1 mitochondrial thiamine pyrophosphate carrier isoform 3
NM_001252396.1 NP_001239325.1 mitochondrial thiamine pyrophosphate carrier isoform 4
NM_026071.3 NP_080347.1 mitochondrial thiamine pyrophosphate carrier isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables thiamine pyrophosphate transmembrane transporter activity IDA
IDA: Inferred from direct assay
17035501 MGI
Biological Process GO Annotation Evidence Reference Source
involved in thiamine diphosphate biosynthetic process IDA
IDA: Inferred from direct assay
8186267 MGI
involved in thiamine diphosphate biosynthetic process IMP
IMP: Inferred from mutant phenotype
17035501 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
17035501 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial thiamine pyrophosphate carrier

solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19

solute carrier family 25 member 19

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13099 SLC25A19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc25a19 NCBI NCBI:60386