Slc25a19 - solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 Gene

Also Known as DNC; TPC; MUP1; 2900089E13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67283

Summary

Predicted to enable thiamine transmembrane transporter activity. Predicted to be involved in thiamine pyrophosphate transmembrane transport. Located in mitochondrion. Is expressed in central nervous system; embryo; retina inner nuclear layer; retina layer; and retina outer nuclear layer. Human ortholog(s) of this gene implicated in inherited metabolic disorder and microcephaly. Orthologous to human SLC25A19 (solute carrier family 25 member 19). [provided by Alliance of Genome Resources, Apr 2022]

Slc25a19 Products (5)

mRNA Protein Name
NM_001252384.1 NP_001239313.1 mitochondrial thiamine pyrophosphate carrier isoform 1
NM_001252394.1 NP_001239323.1 mitochondrial thiamine pyrophosphate carrier isoform 2
NM_001252395.1 NP_001239324.1 mitochondrial thiamine pyrophosphate carrier isoform 3
NM_001252396.1 NP_001239325.1 mitochondrial thiamine pyrophosphate carrier isoform 4
NM_026071.3 NP_080347.1 mitochondrial thiamine pyrophosphate carrier isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables thiamine pyrophosphate transmembrane transporter activity IDA
IDA: Inferred from direct assay
17035501 MGI
Biological Process GO Annotation Evidence References Source
involved in thiamine diphosphate biosynthetic process IDA
IDA: Inferred from direct assay
8186267 MGI
involved in thiamine diphosphate biosynthetic process IMP
IMP: Inferred from mutant phenotype
17035501 MGI
Cellular Component GO Annotation Evidence References Source
is active in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
17035501 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial thiamine pyrophosphate carrier

  • solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19

  • solute carrier family 25 member 19

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13099 SLC25A19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc25a19 NCBI NCBI:60386