C1qtnf12 - C1q and tumor necrosis factor related 12 Gene

Also Known as C1qdc2; CTRP12; Fam132a; alipolin; 1110035L05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67389

Summary

Enables hormone activity. Involved in regulation of glucose import. Acts upstream of or within several processes, including negative regulation of gluconeogenesis; positive regulation of cell communication; and positive regulation of glucose import. Located in extracellular space. Is expressed in cochlea; genitourinary system; liver lobe; thyroid gland; and vibrissa. Orthologous to human C1QTNF12 (C1q and TNF related 12). [provided by Alliance of Genome Resources, Apr 2022]

C1qtnf12 Products (1)

mRNA Protein Name
NM_026125.3 NP_080401.1 adipolin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables hormone activity IDA
IDA: Inferred from direct assay
21849507 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of D-glucose import IMP
IMP: Inferred from mutant phenotype
22275362 MGI
acts upstream of establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
22275362 MGI
acts upstream of gluconeogenesis IDA
IDA: Inferred from direct assay
22275362 MGI
acts upstream of or within negative regulation of gluconeogenesis IDA
IDA: Inferred from direct assay
22275362 MGI
acts upstream of or within negative regulation of inflammatory response IDA
IDA: Inferred from direct assay
21849507 MGI
acts upstream of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: Inferred from direct assay
22275362 MGI
acts upstream of or within positive regulation of D-glucose import IMP
IMP: Inferred from mutant phenotype
22275362 MGI
acts upstream of or within positive regulation of insulin receptor signaling pathway IDA
IDA: Inferred from direct assay
22275362 MGI
acts upstream of or within positive regulation of insulin secretion involved in cellular response to glucose stimulus IDA
IDA: Inferred from direct assay
22275362 MGI
acts upstream of or within positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: Inferred from direct assay
22275362 MGI
involved in regulation of D-glucose import IDA
IDA: Inferred from direct assay
21849507 MGI
acts upstream of or within regulation of glucose metabolic process IDA
IDA: Inferred from direct assay
21849507 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in extracellular region IDA
IDA: Inferred from direct assay
21849507 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
21849507 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adipolin

  • C1q domain containing 2

  • adipose-derived insulin-sensitizing factor

  • complement C1q tumor necrosis factor-related protein 12

  • family with sequence similarity 132, member A

  • protein FAM132A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS01727 C1QTNF12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens C1qtnf12 NCBI NCBI:388581