Tbc1d23 - TBC1 domain family, member 23 Gene

Also Known as 4930451A13Rik; D030022P07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67581

Summary

Involved in embryonic brain development; neuron projection development; and vesicle-mediated transport. Acts upstream of or within positive regulation of interleukin-6 production; regulation of inflammatory response; and regulation of tumor necrosis factor production. Part of WASH complex. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human TBC1D23 (TBC1 domain family member 23). [provided by Alliance of Genome Resources, Apr 2022]

Tbc1d23 Products (3)

mRNA Protein Name
NM_001358433.1 NP_001345362.1 TBC1 domain family member 23 isoform 1
NM_001358434.1 NP_001345363.1 TBC1 domain family member 23 isoform 3
NM_026254.2 NP_080530.2 TBC1 domain family member 23 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
29084197 MGI
Biological Process GO Annotation Evidence References Source
involved in embryonic brain development IMP
IMP: Inferred from mutant phenotype
28823707 MGI
involved in neuron projection development IMP
IMP: Inferred from mutant phenotype
28823707 MGI
acts upstream of or within positive regulation of interleukin-6 production IMP
IMP: Inferred from mutant phenotype
22312129 MGI
acts upstream of or within regulation of inflammatory response IMP
IMP: Inferred from mutant phenotype
22312129 MGI
acts upstream of or within regulation of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
22312129 MGI
involved in vesicle-mediated transport IMP
IMP: Inferred from mutant phenotype
28823707 MGI
Cellular Component GO Annotation Evidence References Source
part of WASH complex IDA
IDA: Inferred from direct assay
29084197 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TBC1 domain family member 23

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14237 TBC1D23 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tbc1d23 NCBI NCBI:55773