2. Gene
  3. Nsmce1 - NSE1 homolog, SMC5-SMC6 complex component Gene

Nsmce1 - NSE1 homolog, SMC5-SMC6 complex component Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2510027N19Rik

Gene ID: 67711 | Gene type: protein coding

About Nsmce1

Summary

Predicted to enable protein dimerization activity and ubiquitin protein Ligase activity. Predicted to be involved in double-strand break repair via homologous recombination; positive regulation of response to DNA damage stimulus; and postreplication repair. Predicted to act upstream of or within DNA recombination and DNA repair. Located in chromosome, centromeric region; mitotic spindle pole; and nucleus. Part of Smc5-Smc6 complex. Is expressed in pancreas epithelium. Orthologous to human NSMCE1 (NSE1 homolog, SMC5-SMC6 complex component). [provided by Alliance of Genome Resources, Apr 2022]

Nsmce1 Products(5)

mRNA Protein Name
NM_001360659.2 NP_001347588.2 non-structural maintenance of chromosomes element 1 homolog isoform 2
NM_001377010.1 NP_001363939.1 non-structural maintenance of chromosomes element 1 homolog isoform 1
NM_001377011.1 NP_001363940.1 non-structural maintenance of chromosomes element 1 homolog isoform 1
NM_001377012.1 NP_001363941.1 non-structural maintenance of chromosomes element 1 homolog isoform 2
NM_026330.4 NP_080606.3 non-structural maintenance of chromosomes element 1 homolog isoform 1
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
part of Smc5-Smc6 complex IDA
IDA: Inferred from direct assay
26919979 MGI
located in chromosome, centromeric region IDA
IDA: Inferred from direct assay
26919979 MGI
located in mitotic spindle pole IDA
IDA: Inferred from direct assay
26919979 MGI
located in nucleus IDA
IDA: Inferred from direct assay
26919979 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

non-structural maintenance of chromosomes element 1 homolog

non-SMC element 1 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09597 NSMCE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nsmce1 NCBI NCBI:197370