Jagn1 - jagunal homolog 1 Gene

Also Known as 5830427H10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67767

Summary

Involved in several processes, including defense response to fungus; granulocyte colony-stimulating factor signaling pathway; and neutrophil migration. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Is expressed in basisphenoid bone; dorsal root ganglion; orbito-sphenoid; submandibular gland primordium; and turbinate bone primordium. Human ortholog(s) of this gene implicated in severe congenital neutropenia 6. Orthologous to human JAGN1 (jagunal homolog 1). [provided by Alliance of Genome Resources, Apr 2022]

Jagn1 Products (3)

mRNA Protein Name
NM_001205025.1 NP_001191954.1 protein jagunal homolog 1 isoform 2
NM_001243739.1 NP_001230668.1 protein jagunal homolog 1 isoform 3
NM_026365.3 NP_080641.1 protein jagunal homolog 1 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in defense response to fungus IMP
IMP: Inferred from mutant phenotype
25129145 MGI
involved in granulocyte colony-stimulating factor signaling pathway IMP
IMP: Inferred from mutant phenotype
25129145 MGI
NOT involved in neutrophil differentiation IMP
IMP: Inferred from mutant phenotype
25129145 MGI
involved in neutrophil mediated immunity IMP
IMP: Inferred from mutant phenotype
25129145 MGI
involved in neutrophil migration IMP
IMP: Inferred from mutant phenotype
25129145 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein jagunal homolog 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07014 JAGN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Jagn1 NCBI NCBI:84522