LRRTM1 - leucine rich repeat transmembrane neuronal 1 Gene

Rattus norvegicus

Gene ID: 679668 | Gene type: protein coding

About LRRTM1

Summary

Involved in regulation of postsynaptic density assembly and regulation of presynapse assembly. Acts upstream of or within synapse organization. Located in excitatory synapse. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane. Orthologous to human LRRTM1 (leucine rich repeat transmembrane neuronal 1). [provided by Alliance of Genome Resources, Apr 2022]

LRRTM1 Products(1)

mRNA	Protein	Name
NM_001395622.1	NP_001382551.1	leucine-rich repeat transmembrane neuronal protein 1 precursor

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in regulation of postsynaptic density assembly	IDA IDA: Inferred from direct assay	19285470	RGD
involved in regulation of postsynaptic density assembly	IMP IMP: Inferred from mutant phenotype	19285470	RGD
involved in regulation of presynapse assembly	IDA IDA: Inferred from direct assay	19285470	RGD
involved in regulation of presynapse assembly	IMP IMP: Inferred from mutant phenotype	19285470	RGD
acts upstream of or within synapse organization	IDA IDA: Inferred from direct assay	19285470	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in excitatory synapse	IDA IDA: Inferred from direct assay	19285470	RGD
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	19285470	RGD
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	19285470	RGD
is active in postsynaptic membrane	IDA IDA: Inferred from direct assay	19285470	RGD
is active in postsynaptic membrane	IMP IMP: Inferred from mutant phenotype	19285470	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

leucine-rich repeat transmembrane neuronal protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07841	LRRTM1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	LRRTM1	NCBI	NCBI:347730

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