Mad1l1 - mitotic arrest deficient 1 like 1 Gene

About Mad1l1

Summary

Predicted to enable identical protein binding activity and kinetochore binding activity. Predicted to be involved in several processes, including attachment of mitotic spindle microtubules to kinetochore; cytoplasmic sequestering of protein; and regulation of mitotic metaphase/anaphase transition. Predicted to act upstream of or within negative regulation of T cell proliferation; regulation of mitotic cell cycle phase transition; and thymus development. Predicted to be located in cytoplasm; nucleus; and spindle pole. Predicted to be part of nuclear pore nuclear basket. Predicted to be active in kinetochore; mitotic spindle; and nuclear envelope. Predicted to colocalize with mitotic spindle pole. Human ortholog(s) of this gene implicated in lymphoma and prostate Cancer. Orthologous to human MAD1L1 (mitotic arrest deficient 1 like 1). [provided by Alliance of Genome Resources, Apr 2022]