Coa8 - cytochrome c oxidase assembly factor 8 Gene

Also Known as Apop1; Apop-1; Apopt1; 1700081D05Rik; 2810002N01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68020

Summary

Involved in several processes, including mitochondrial cytochrome c oxidase assembly; positive regulation of cytochrome-c oxidase activity; and protein stabilization. Acts upstream of or within intrinsic apoptotic signaling pathway. Located in mitochondrion. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human COA8 (cytochrome c oxidase assembly factor 8). [provided by Alliance of Genome Resources, Apr 2022]

Coa8 Products (2)

mRNA Protein Name
NM_001163388.1 NP_001156860.1 cytochrome c oxidase assembly factor 8 isoform 1
NM_026511.2 NP_080787.1 cytochrome c oxidase assembly factor 8 isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within intrinsic apoptotic signaling pathway IDA
IDA: Inferred from direct assay
16782708 MGI
involved in mitochondrial cytochrome c oxidase assembly IDA
IDA: Inferred from direct assay
30552096 MGI
involved in positive regulation of cytochrome-c oxidase activity IDA
IDA: Inferred from direct assay
30552096 MGI
involved in protein stabilization IDA
IDA: Inferred from direct assay
30552096 MGI
involved in response to reactive oxygen species IDA
IDA: Inferred from direct assay
30552096 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
16782708 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome c oxidase assembly factor 8

  • UPF0671 protein C14orf153 homolog

  • apoptogenic protein 1, mitochondrial

  • apoptogenic, mitochondrial 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (34)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-CE00430 (8Z,11Z)-Icosadienoyl-CoA / Unkown
HY-CE00431 (8Z,11Z,14Z)-3-Oxoicosa-8,11,14-trienoyl-CoA / Unkown
HY-CE00434 (8Z,11Z,14Z,17Z)-3-Oxoicosatetraenoyl-CoA / Unkown
HY-CE00437 (8Z,11Z,14Z,17Z)-Icosatetraenoyl-CoA / Unkown
HY-CE00439 (8Z,11Z,14Z,17Z,20Z)-Hexacosapentaenoyl-CoA / Unkown
HY-CE00441 (8Z,11Z,14Z,17Z,20Z,23Z)-3-Oxohexacosahexaenoyl-CoA / Unkown
HY-CE00443 (8Z,11Z,14Z,17Z,20Z,23Z)-Hexacosahexaenoyl-CoA / Unkown
HY-CE01319 8-Hydroxyhexadecanoyl-CoA / Unkown
HY-CE01363 8-Hydroxydecanoyl-CoA / Unkown
HY-CE01364 8-Hydroxydodecanoyl-CoA / Unkown
HY-CE01365 8-Hydroxyundecanoyl-CoA / Unkown
HY-CE01366 8-Methyl-6-nonenoyl-CoA / Unkown
HY-CE01367 8-MethylHexadecanoyl-CoA / Unkown
HY-CE01368 8-Methyldecanoyl-CoA / Unkown
HY-CE01369 8-Methyldocosanoyl-CoA / Unkown
HY-CE01370 8-Methyldodecanoyl-CoA / Unkown
HY-CE01371 8-Methylhenicosanoyl-CoA / Unkown
HY-CE01372 8-Methylheptadecanoyl-CoA / Unkown
HY-CE01373 8-Methylicosanoyl-CoA / Unkown
HY-CE01375 8-Methyloctadecanoyl-CoA / Unkown
HY-CE01376 8-Methylpentacosanoyl-CoA / Unkown
HY-CE01377 8-Methylpentadecanoyl-CoA / Unkown
HY-CE01378 8-Methyltetracosanoyl-CoA / Unkown
HY-CE01379 8-Methyltetradecanoyl-CoA / Unkown
HY-CE01380 8-Methyltricosanoyl-CoA / Unkown
HY-CE01381 8-Methyltridecanoyl-CoA / Unkown
HY-CE01382 8-Methylundecanoyl-CoA / Unkown
HY-CE01383 8-Oxodecanoyl-CoA / Unkown
HY-CE01443 8-Hydroxyoctadecanoyl-CoA / Unkown
HY-CE01444 8-Methylnonadecanoyl-CoA / Unkown
HY-CE01559 8-Oxononanoyl-CoA / Unkown
HY-CE01561 8-Hydroxyhexadecanedioyl-CoA / Unkown
HY-CE01628 OPC-8-CoA / Unkown
HY-RS02945 COA8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Coa8 NCBI NCBI:84334