2. Gene
  3. Arl13b - ADP-ribosylation factor-like 13B Gene

Arl13b - ADP-ribosylation factor-like 13B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as hnn; Arl2l1; A530097K21Rik; A930014M17Rik; C530009C10Rik

Gene ID: 68146 | Gene type: protein coding

About Arl13b

Summary

Predicted to enable GTP binding activity. Involved in nervous system development; non-motile cilium assembly; and smoothened signaling pathway. Acts upstream of or within dorsal/ventral pattern formation; heart looping; and left/right axis specification. Located in axoneme; ciliary membrane; and motile cilium. Is expressed in several structures, including chordamesoderm; embryo mesenchyme; future spinal cord; lateral ventricle; and node. Human ortholog(s) of this gene implicated in Joubert syndrome 8. Orthologous to human ARL13B (ADP ribosylation factor like GTPase 13B). [provided by Alliance of Genome Resources, Apr 2022]

Arl13b Products(1)

mRNA Protein Name
NM_026577.4 NP_080853.3 ADP-ribosylation factor-like protein 13B
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
26582389 MGI
Biological Process GO Annotation Evidence Reference Source
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
17488627 MGI
acts upstream of or within determination of left/right symmetry IMP
IMP: Inferred from mutant phenotype
15755804 MGI
acts upstream of or within dorsal/ventral pattern formation IMP
IMP: Inferred from mutant phenotype
15755804 MGI
involved in formation of radial glial scaffolds IMP
IMP: Inferred from mutant phenotype
23817546 MGI
acts upstream of or within heart looping IMP
IMP: Inferred from mutant phenotype
22554696 MGI
involved in interneuron migration from the subpallium to the cortex IMP
IMP: Inferred from mutant phenotype
23153492 MGI
acts upstream of or within left/right axis specification IMP
IMP: Inferred from mutant phenotype
22554696 MGI
involved in neural tube patterning IMP
IMP: Inferred from mutant phenotype
23014696 MGI
involved in non-motile cilium assembly IMP
IMP: Inferred from mutant phenotype
21976698 MGI
involved in smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
17488627 MGI
Cellular Component GO Annotation Evidence Reference Source
located in axoneme IDA
IDA: Inferred from direct assay
21209331 MGI
located in ciliary membrane IDA
IDA: Inferred from direct assay
21976698 MGI
located in cilium IDA
IDA: Inferred from direct assay
17488627 MGI
located in motile cilium IDA
IDA: Inferred from direct assay
24336288 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ADP-ribosylation factor-like protein 13B

ADP-ribosylation factor-like 2-like 1

ARL2-like protein 1

protein hennin

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00980 ARL13B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arl13b NCBI NCBI:200894