Dubr - Dppa2 upstream binding RNA Gene

Mus musculus

Also known as Dum; 5330426P16Rik

Gene ID: 68190 | Gene type: ncRNA

About Dubr

Summary

Acts upstream of or within negative regulation of transcription by RNA polymerase II; positive regulation of myoblast differentiation; and regulation of DNA methylation. Located in cytoplasm and nucleus. Is expressed in central nervous system and dorsal root ganglion. Orthologous to human DUBR (DPPA2 upstream binding RNA). [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25686699	MGI
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	37494937	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within axonogenesis	IMP IMP: Inferred from mutant phenotype	37494937	MGI
acts upstream of or within central nervous system neuron axonogenesis	IMP IMP: Inferred from mutant phenotype	37494937	MGI
acts upstream of or within gene expression	IMP IMP: Inferred from mutant phenotype	37494937	MGI
acts upstream of or within negative regulation of gene expression via chromosomal CpG island methylation	IMP IMP: Inferred from mutant phenotype	25686699	MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	25686699	MGI
acts upstream of or within neuron development	IMP IMP: Inferred from mutant phenotype	37494937	MGI
acts upstream of or within neuron migration	IMP IMP: Inferred from mutant phenotype	37494937	MGI
acts upstream of or within positive regulation of myoblast differentiation	IMP IMP: Inferred from mutant phenotype	25686699	MGI
acts upstream of or within protein stabilization	IMP IMP: Inferred from mutant phenotype	37494937	MGI
acts upstream of or within translation	IMP IMP: Inferred from mutant phenotype	37494937	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in cytoplasm	IDA IDA: Inferred from direct assay	37494937	MGI
located in cytoplasm	IDA IDA: Inferred from direct assay	25686699	MGI
is active in nucleus	IDA IDA: Inferred from direct assay	37494937	MGI
located in nucleus	IDA IDA: Inferred from direct assay	25686699	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dubr	NCBI	NCBI:344595

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