Dubr - Dppa2 upstream binding RNA Gene

Also Known as Dum; 5330426P16Rik

Species: Mus musculus

Gene Type: ncRNA
Gene ID: 68190

Summary

Acts upstream of or within negative regulation of transcription by RNA polymerase II; positive regulation of myoblast differentiation; and regulation of DNA methylation. Located in cytoplasm and nucleus. Is expressed in central nervous system and dorsal root ganglion. Orthologous to human DUBR (DPPA2 upstream binding RNA). [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25686699 MGI
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
37494937 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within axonogenesis IMP
IMP: Inferred from mutant phenotype
37494937 MGI
acts upstream of or within central nervous system neuron axonogenesis IMP
IMP: Inferred from mutant phenotype
37494937 MGI
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
37494937 MGI
acts upstream of or within negative regulation of gene expression via chromosomal CpG island methylation IMP
IMP: Inferred from mutant phenotype
25686699 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
25686699 MGI
acts upstream of or within neuron development IMP
IMP: Inferred from mutant phenotype
37494937 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
37494937 MGI
acts upstream of or within positive regulation of myoblast differentiation IMP
IMP: Inferred from mutant phenotype
25686699 MGI
acts upstream of or within protein stabilization IMP
IMP: Inferred from mutant phenotype
37494937 MGI
acts upstream of or within translation IMP
IMP: Inferred from mutant phenotype
37494937 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytoplasm IDA
IDA: Inferred from direct assay
37494937 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
25686699 MGI
is active in nucleus IDA
IDA: Inferred from direct assay
37494937 MGI
located in nucleus IDA
IDA: Inferred from direct assay
25686699 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Orthologs Information

Species Symbol Source ID
Homo sapiens Dubr NCBI NCBI:344595