Ndufs3 - NADH:ubiquinone oxidoreductase core subunit S3 Gene

Also Known as CI-30kD; 0610010M09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68349

Summary

Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Part of mitochondrial respiratory chain complex I. Is expressed in several structures, including alimentary system; ear; genitourinary system; integumental system; and nervous system. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 8. Orthologous to human NDUFS3 (NADH:ubiquinone oxidoreductase core subunit S3). [provided by Alliance of Genome Resources, Apr 2022]

Ndufs3 Products (1)

mRNA Protein Name
NM_026688.3 NP_080964.1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables NADH dehydrogenase (ubiquinone) activity IMP
IMP: Inferred from mutant phenotype
31916679 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
31536960 MGI
Biological Process GO Annotation Evidence References Source
involved in mitochondrial electron transport, NADH to ubiquinone IMP
IMP: Inferred from mutant phenotype
31916679 MGI
involved in mitochondrial respiratory chain complex I assembly IMP
IMP: Inferred from mutant phenotype
31916679 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
19837698 MGI
part of respiratory chain complex I IDA
IDA: Inferred from direct assay
18396137 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

  • NADH-ubiquinone oxidoreductase 30 kDa subunit

  • complex I-30kD

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09159 NDUFS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ndufs3 NCBI NCBI:4722