Nsmce2 - NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase Gene
Also Known as 1110014D18Rik
Species: Mus musculus
Summary
Predicted to enable SUMO Ligase activity. Predicted to be involved in several processes, including DNA recombination; positive regulation of cell cycle process; and protein sumoylation. Predicted to act upstream of or within DNA recombination; DNA repair; and cell division. Predicted to be located in PML body and chromosome, telomeric region. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Is expressed in brain; spermatocyte; and testis. Used to study Bloom syndrome. Human ortholog(s) of this gene implicated in Seckel syndrome 10. Orthologous to human NSMCE2 (NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO Ligase). [provided by Alliance of Genome Resources, Apr 2022]
Nsmce2 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001164604.1 | NP_001158076.1 | E3 SUMO-protein ligase NSE2 isoform 2 |
| NM_001374768.1 | NP_001361697.1 | E3 SUMO-protein ligase NSE2 isoform 3 |
| NM_026746.3 | NP_081022.2 | E3 SUMO-protein ligase NSE2 isoform 1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
E3 SUMO-protein ligase NSE2 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS09598 | NSMCE2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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