Ints1 - integrator complex subunit 1 Gene

Also Known as 1110015K06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68510

Summary

Acts upstream of or within U2 snRNA 3'-end processing; inner cell mass cell proliferation; and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process. Located in nucleus. Is expressed in early conceptus. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies. Orthologous to human INTS1 (integrator complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Ints1 Products (1)

mRNA Protein Name
NM_026748.3 NP_081024.4 integrator complex subunit 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within U2 snRNA 3'-end processing IMP
IMP: Inferred from mutant phenotype
17544522 MGI
acts upstream of or within blastocyst growth IMP
IMP: Inferred from mutant phenotype
17544522 MGI
acts upstream of or within embryo implantation IMP
IMP: Inferred from mutant phenotype
16807365 MGI
acts upstream of or within inner cell mass cell proliferation IMP
IMP: Inferred from mutant phenotype
17544522 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
17544522 MGI
acts upstream of or within negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
17544522 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
17544522 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrator complex subunit 1

  • int1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06850 INTS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-114541 Coumarin-7-pinacolboronate / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ints1 NCBI NCBI:26173