Elac2 - elaC ribonuclease Z 2 Gene

Also Known as Hpc2; D11Wsu80e; 1110017O07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68626

Summary

Predicted to enable 3'-tRNA processing endoribonuclease activity and tRNA-specific ribonuclease activity. Predicted to be involved in mitochondrial tRNA 3'-trailer cleavage, endonucleolytic. Located in mitochondrial nucleoid. Is expressed in extraembryonic component. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency 17. Orthologous to human ELAC2 (elaC ribonuclease Z 2). [provided by Alliance of Genome Resources, Apr 2022]

Elac2 Products (4)

mRNA Protein Name
NM_001362982.1 NP_001349911.1 zinc phosphodiesterase ELAC protein 2 isoform 2
NM_001362983.1 NP_001349912.1 zinc phosphodiesterase ELAC protein 2 isoform 3
NM_001362984.1 NP_001349913.1 zinc phosphodiesterase ELAC protein 2 isoform 4
NM_023479.3 NP_075968.2 zinc phosphodiesterase ELAC protein 2 isoform 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in mitochondrial nucleoid IDA
IDA: Inferred from direct assay
24703694 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc phosphodiesterase ELAC protein 2

  • RNase Z 2

  • elaC homolog 2

  • elaC homolog protein 2

  • putative prostate cancer susceptibility protein

  • ribonuclease Z 2

  • tRNA 3 endonuclease 2

  • tRNase Z 2

  • tRNase Z(L)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04291 ELAC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Elac2 NCBI NCBI:60528