Ric3 - RIC3 acetylcholine receptor chaperone Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 687147

Summary

Enables acetylcholine receptor binding activity. Acts upstream of or within cholinergic synaptic transmission and positive regulation of cytosolic calcium ion concentration. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle; neuron projection; and neuronal cell body. Orthologous to human RIC3 (RIC3 acetylcholine receptor chaperone). [provided by Alliance of Genome Resources, Apr 2022]

Ric3 Products (2)

mRNA Protein Name
NM_001115045.3 NP_001108517.1 protein RIC-3 isoform 1
NM_001277069.1 NP_001263998.1 protein RIC-3 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables acetylcholine receptor binding IDA
IDA: Inferred from direct assay
18420419 RGD
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of cytosolic calcium ion concentration IGI
IGI: Inferred from genetic interaction
18420419 RGD
acts upstream of or within synaptic transmission, cholinergic IGI
IGI: Inferred from genetic interaction
18420419 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein RIC-3

  • putative alpha7-nAChR chaperone

  • resistance to inhibitors of cholinesterase 3 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11966 RIC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ric3 NCBI NCBI:79608