Synpo2l - synaptopodin 2-like Gene

Also Known as Chap; 1110054M18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68760

Summary

Predicted to enable actin binding activity. Involved in several processes, including positive regulation of Rho protein signal transduction; positive regulation of stress fiber assembly; and sarcomere organization. Located in Z disc and nucleus. Is expressed in several structures, including diaphragm; heart; limb mesenchyme; myotome; and skeletal musculature. Orthologous to human SYNPO2L (synaptopodin 2 like). [provided by Alliance of Genome Resources, Apr 2022]

Synpo2l Products (3)

mRNA Protein Name
NM_001310431.1 NP_001297360.1 synaptopodin 2-like protein isoform 1
NM_001310432.1 NP_001297361.1 synaptopodin 2-like protein isoform 3
NM_175132.4 NP_780341.1 synaptopodin 2-like protein isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20215401 MGI
Biological Process GO Annotation Evidence References Source
involved in heart morphogenesis IMP
IMP: Inferred from mutant phenotype
29206857 MGI
involved in positive regulation of Rho protein signal transduction IMP
IMP: Inferred from mutant phenotype
29206857 MGI
involved in positive regulation of stress fiber assembly IMP
IMP: Inferred from mutant phenotype
29206857 MGI
involved in sarcomere organization IMP
IMP: Inferred from mutant phenotype
29206857 MGI
Cellular Component GO Annotation Evidence References Source
located in Z disc IDA
IDA: Inferred from direct assay
20215401 MGI
located in nucleus IDA
IDA: Inferred from direct assay
20215401 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptopodin 2-like protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14099 SYNPO2L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Synpo2l NCBI NCBI:79933