2. Gene
  3. Mypn - myopalladin Gene

Mypn - myopalladin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA4170; 9830112J03; 1110056A04Rik

Gene ID: 68802 | Gene type: protein coding

About Mypn

Summary

Predicted to enable SH3 domain binding activity; cell-cell adhesion mediator activity; and muscle alpha-actinin binding activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules; neuron development; and sarcomere organization. Located in I band. Colocalizes with Z disc. Is expressed in diaphragm; eye; heart; tongue muscle; and vertebral axis musculature. Used to study nemaline myopathy 11 and restrictive cardiomyopathy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1KK and nemaline myopathy 11. Orthologous to human MYPN (myopalladin). [provided by Alliance of Genome Resources, Apr 2022]

Mypn Products(1)

mRNA Protein Name
NM_182992.2 NP_892037.2 myopalladin
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in I band IDA
IDA: Inferred from direct assay
11309420 MGI
colocalizes with Z disc IDA
IDA: Inferred from direct assay
11309420 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myopalladin

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08967 MYPN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mypn NCBI NCBI:84665