2. Gene
  3. PDE6G - Pde6g phosphodiesterase 6G Gene

PDE6G - Pde6g phosphodiesterase 6G Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 688297 | Gene type: protein coding

About PDE6G

Summary

Enables spectrin binding activity. Predicted to be involved in positive regulation of G protein-coupled receptor signaling pathway and positive regulation of epidermal growth factor receptor signaling pathway. Predicted to act upstream of or within positive regulation of MAPK cascade. Predicted to be active in photoreceptor outer segment membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa 57. Orthologous to human PDE6G (phosphodiesterase 6G). [provided by Alliance of Genome Resources, Apr 2022]

PDE6G Products(2)

mRNA Protein Name
NM_001398947.1 NP_001385876.1 phosphodiesterase 6G
NM_001398948.1 NP_001385877.1 phosphodiesterase 6G
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables spectrin binding IDA
IDA: Inferred from direct assay
23704327 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphodiesterase 6G

retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

phosphodiesterase 6G, cGMP-specific, rod, gamma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10236 PDE6G Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PDE6G NCBI NCBI:5148