2. Gene
  3. Tmco1 - transmembrane and coiled-coil domains 1 Gene

Tmco1 - transmembrane and coiled-coil domains 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ESTM39; 1190006A08Rik; 4930403O06Rik

Gene ID: 68944 | Gene type: protein coding

About Tmco1

Summary

Predicted to enable Calcium Channel activity and ribosome binding activity. Involved in calcium ion transmembrane transport and endoplasmic reticulum calcium ion homeostasis. Predicted to be integral component of endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Is expressed in clavicle; mandible; maxilla; and rib. Orthologous to human TMCO1 (transmembrane and coiled-coil domains 1). [provided by Alliance of Genome Resources, Apr 2022]

Tmco1 Products(1)

mRNA Protein Name
NM_001039483.1 NP_001034572.1 calcium load-activated calcium channel precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in calcium ion transmembrane transport IMP
IMP: Inferred from mutant phenotype
27212239 MGI
involved in endoplasmic reticulum calcium ion homeostasis IMP
IMP: Inferred from mutant phenotype
27212239 MGI
involved in ossification IMP
IMP: Inferred from mutant phenotype
30962442 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcium load-activated calcium channel

CLAC channel

transmembrane and coiled-coil domain-containing protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14632 TMCO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmco1 NCBI NCBI:54499