Kmt2e - lysine (K)-specific methyltransferase 2E Gene

Also Known as Mll5; NKp44L; 1810033J14Rik; 9530077A04Rik; D230038D11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69188

Summary

Predicted to enable enzyme binding activity and methylated histone binding activity. Involved in several processes, including DNA methylation; erythrocyte differentiation; and neutrophil activation. Predicted to be located in nuclear body and transcriptionally active chromatin. Predicted to be part of protein-containing complex. Is expressed in several structures, including alimentary system; eye; heart; metanephros; and nervous system. Human ortholog(s) of this gene implicated in autistic disorder and cervical Cancer. Orthologous to human KMT2E (lysine methyltransferase 2E (inactive)). [provided by Alliance of Genome Resources, Apr 2022]

Kmt2e Products (1)

mRNA Protein Name
NM_026984.2 NP_081260.1 inactive histone-lysine N-methyltransferase 2E

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in epigenetic regulation of gene expression IMP
IMP: Inferred from mutant phenotype
18854576 MGI
involved in erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
18854576 MGI
involved in neutrophil activation IMP
IMP: Inferred from mutant phenotype
18854576 MGI
involved in neutrophil mediated immunity IMP
IMP: Inferred from mutant phenotype
18854576 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inactive histone-lysine N-methyltransferase 2E

  • histone-lysine N-methyltransferase MLL5

  • myeloid/lymphoid or mixed-lineage leukemia protein 5 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07405 KMT2E Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kmt2e NCBI NCBI:55904