Esco2 - establishment of sister chromatid cohesion N-acetyltransferase 2 Gene

Predicted to enable lysine N-acetyltransferase activity, acting on acetyl phosphate as donor. Predicted to be involved in post-translational protein acetylation; regulation of DNA replication; and sister chromatid cohesion. Predicted to act upstream of or within several processes, including double-strand break repair; hematopoietic progenitor cell differentiation; and protein localization to chromatin. Predicted to be located in several cellular components, including Golgi apparatus; chromocenter; and chromosome. Human ortholog(s) of this gene implicated in Roberts syndrome. Orthologous to human ESCO2 (establishment of sister chromatid cohesion N-acetyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]