Pierce1 - piercer of microtubule wall 1 Gene

Mus musculus

Also known as Rbest47; 1700007K13Rik

Gene ID: 69327 | Gene type: protein coding

About Pierce1

Summary

Acts upstream of or within several processes, including cellular response to DNA damage stimulus; cellular response to UV-C; and determination of left/right symmetry. Located in nucleus. Is expressed in brain; genitourinary system; lung; node; and retina. Orthologous to human C9orf116 (chromosome 9 open reading frame 116). [provided by Alliance of Genome Resources, Apr 2022]

Pierce1 Products(1)

mRNA	Protein	Name
NM_027040.1	NP_081316.1	piercer of microtubule wall 1 protein

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within DNA damage response	IMP IMP: Inferred from mutant phenotype	21159655	MGI
involved in axoneme assembly	IMP IMP: Inferred from mutant phenotype	34715025	MGI
acts upstream of or within cellular response to UV-C	IMP IMP: Inferred from mutant phenotype	21159655	MGI
involved in cilium movement	IMP IMP: Inferred from mutant phenotype	34715025	MGI
acts upstream of or within determination of left/right symmetry	IMP IMP: Inferred from mutant phenotype	27305836	MGI
involved in determination of left/right symmetry	IMP IMP: Inferred from mutant phenotype	34715025	MGI
involved in establishment of left/right asymmetry	IMP IMP: Inferred from mutant phenotype	27305836	MGI
involved in flagellated sperm motility	IDA IDA: Inferred from direct assay	37295417	MGI
acts upstream of or within regulation of gene expression	IMP IMP: Inferred from mutant phenotype	21159655	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in axonemal A tubule inner sheath	IDA IDA: Inferred from direct assay	37295417	MGI
located in cytoplasm	IDA IDA: Inferred from direct assay	27305836	MGI
located in nucleus	IDA IDA: Inferred from direct assay	27305836	MGI
located in nucleus	IMP IMP: Inferred from mutant phenotype	27305836	MGI
is active in sperm flagellum	IDA IDA: Inferred from direct assay	37295417	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

piercer of microtubule wall 1 protein

UPF0691 protein C9orf116 homolog	p53-induced expression in RB-null cells protein 1
pierce 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10482	PIERCE1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pierce1	NCBI	NCBI:138162

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