Afg3l2 - AFG3-like AAA ATPase 2 Gene

Also Known as par; Emv66; 2310036I02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69597

Summary

Predicted to enable metalloendopeptidase activity. Involved in protein autoprocessing. Acts upstream of or within several processes, including mitochondrion organization; nervous system development; and righting reflex. Located in mitochondrial inner membrane. Part of m-AAA complex. Is expressed in brain. Used to study spinocerebellar ataxia type 28. Human ortholog(s) of this gene implicated in optic atrophy 12; spastic ataxia; spastic ataxia 5; and spinocerebellar ataxia type 28. Orthologous to human AFG3L2 (AFG3 like matrix AAA peptidase subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Afg3l2 Products (1)

mRNA Protein Name
NM_027130.2 NP_081406.1 AFG3-like protein 2
Protein Preferred Names Protein Names

AFG3-like protein 2

  • AFG3 (ATPase family gene 3)-like 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00432 AFG3L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Afg3l2 NCBI NCBI:10939