Exosc8 - exosome component 8 Gene

Also Known as CIP3; mKIAA4013; 2310032N20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69639

Summary

Predicted to enable identical protein binding activity and mRNA 3'-UTR AU-rich region binding activity. Predicted to be involved in RNA metabolic process. Predicted to act upstream of or within rRNA processing. Predicted to be located in chromosome; cytosol; and nuclear lumen. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and integumental system. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human EXOSC8 (exosome component 8). [provided by Alliance of Genome Resources, Apr 2022]

Exosc8 Products (2)

mRNA Protein Name
NM_001163570.2 NP_001157042.1 exosome complex component RRP43 isoform 1
NM_027148.4 NP_081424.3 exosome complex component RRP43 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22693585 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

exosome complex component RRP43

  • exosome complex exonuclease RRP43

  • ribosomal RNA-processing protein 43

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04604 EXOSC8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Exosc8 NCBI NCBI:11340