Dctn2 - dynactin 2 Gene

Also Known as p50; RBP50; DCTN-50; GMP23-48K; 2310042E05Rik; C130077D06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69654

Summary

Predicted to enable identical protein binding activity; protein kinase binding activity; and spectrin binding activity. Acts upstream of or within melanosome transport. Located in growth cone. Is expressed in several structures, including adipose tissue; alimentary system; early conceptus; genitourinary system; and nervous system. Orthologous to human DCTN2 (dynactin subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Dctn2 Products (3)

mRNA Protein Name
NM_001190453.1 NP_001177382.1 dynactin subunit 2 isoform 2
NM_001190454.1 NP_001177383.1 dynactin subunit 2 isoform 1
NM_027151.2 NP_081427.1 dynactin subunit 2 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11483508 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within melanosome transport IMP
IMP: Inferred from mutant phenotype
22275436 MGI
Cellular Component GO Annotation Evidence References Source
located in growth cone IDA
IDA: Inferred from direct assay
9144527 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dynactin subunit 2

  • 50 kDa dynein-associated polypeptide

  • dynactin complex 50 kDa subunit

  • growth cone membrane protein 23-48K

  • p50 dynamitin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03594 DCTN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dctn2 NCBI NCBI:10540