2. Gene
  3. Nkiras1 - NFKB inhibitor interacting Ras-like protein 1 Gene

Nkiras1 - NFKB inhibitor interacting Ras-like protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as KBRAS1; kappaB-Ras1; 2400004O09Rik

Gene ID: 69721 | Gene type: protein coding

About Nkiras1

Summary

Enables GTPase activating protein binding activity. Acts upstream of or within several processes, including Ral protein signal transduction; lung alveolus development; and surfactant homeostasis. Predicted to be located in cytosol and endoplasmic reticulum. Orthologous to human NKIRAS1 (NFKB inhibitor interacting Ras like 1). [provided by Alliance of Genome Resources, Apr 2022]

Nkiras1 Products(3)

mRNA Protein Name
NM_001316711.1 NP_001303640.1 NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform 2
NM_001316712.1 NP_001303641.1 NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform 3
NM_023526.4 NP_076015.2 NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables GTPase activating protein binding IPI
IPI: Inferred from physical interaction
25220458 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within Ral protein signal transduction IGI
IGI: Inferred from genetic interaction
25220458 MGI
acts upstream of or within lung alveolus development IGI
IGI: Inferred from genetic interaction
25220458 MGI
acts upstream of or within regulation of tumor necrosis factor-mediated signaling pathway IGI
IGI: Inferred from genetic interaction
25220458 MGI
acts upstream of or within surfactant homeostasis IGI
IGI: Inferred from genetic interaction
25220458 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NF-kappa-B inhibitor-interacting Ras-like protein 1

I-kappa-B-interacting Ras-like protein 1

kappa B-Ras protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09320 NKIRAS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nkiras1 NCBI NCBI:28512