Rnaseh2a - ribonuclease H2, large subunit Gene

Also Known as RNHL; RNHIA; RNASEHI; 2400006P09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69724

Summary

Predicted to enable RNA-DNA hybrid ribonuclease activity. Acts upstream of or within mismatch repair. Part of ribonuclease H2 complex. Is expressed in several structures, including embryo ectoderm; gut; hemolymphoid system gland; skin; and testis. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human RNASEH2A (ribonuclease H2 subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Rnaseh2a Products (2)

mRNA Protein Name
NM_001364370.1 NP_001351299.1 ribonuclease H2 subunit A isoform 2
NM_027187.4 NP_081463.1 ribonuclease H2 subunit A isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within mismatch repair IMP
IMP: Inferred from mutant phenotype
23603115 MGI
Cellular Component GO Annotation Evidence References Source
part of ribonuclease H2 complex IDA
IDA: Inferred from direct assay
19923215 MGI
part of ribonuclease H2 complex IPI
IPI: Inferred from physical interaction
19923215 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ribonuclease H2 subunit A

  • RNase H2 subunit A

  • RNase HI large subunit

  • ribonuclease HI large subunit

  • ribonuclease HI subunit A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12025 RNASEH2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnaseh2a NCBI NCBI:10535