Pcgf1 - polycomb group ring finger 1 Gene

Also Known as Nspc1; 2010002K04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69837

Summary

Predicted to enable promoter-specific chromatin binding activity and protein C-terminus binding activity. Predicted to be involved in heterochromatin assembly; histone H2A-K119 monoubiquitination; and negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of PcG protein complex. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; nervous system; and striated muscle tissue. Orthologous to human PCGF1 (polycomb group ring finger 1). [provided by Alliance of Genome Resources, Apr 2022]

Pcgf1 Products (5)

mRNA Protein Name
NM_001403558.1 NP_001390487.1 polycomb group RING finger protein 1 isoform 2
NM_001403559.1 NP_001390488.1 polycomb group RING finger protein 1 isoform 3
NM_001403560.1 NP_001390489.1 polycomb group RING finger protein 1 isoform 3
NM_001403561.1 NP_001390490.1 polycomb group RING finger protein 1 isoform 3
NM_197992.2 NP_932109.2 polycomb group RING finger protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28596365 MGI
Cellular Component GO Annotation Evidence References Source
part of PcG protein complex IDA
IDA: Inferred from direct assay
28596365 MGI
located in nucleus IDA
IDA: Inferred from direct assay
28596365 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polycomb group RING finger protein 1

  • RING finger protein 68

  • nervous system Polycomb-1

  • nervous system polycomb 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-170823 PRC1-IN-1 Inhibitor 97.30% Unkown
HY-RS10145 PCGF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pcgf1 NCBI NCBI:84759