2. Gene
  3. Fars2 - phenylalanine-tRNA synthetase 2 (mitochondrial) Gene

Fars2 - phenylalanine-tRNA synthetase 2 (mitochondrial) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Fars1; pheRS

Gene ID: 69955 | Gene type: protein coding

About Fars2

Summary

Predicted to enable phenylalanine-tRNA Ligase activity and tRNA binding activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation and tRNA processing. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency 14 and hereditary spastic paraplegia 77. Orthologous to human FARS2 (phenylalanyl-tRNA synthetase 2, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Fars2 Products(2)

mRNA Protein Name
NM_001039189.2 NP_001034278.1 phenylalanine--tRNA ligase, mitochondrial isoform 2
NM_024274.3 NP_077236.1 phenylalanine--tRNA ligase, mitochondrial isoform 1
Protein Preferred Names Protein Names

phenylalanine--tRNA ligase, mitochondrial

phenylalanine-tRNA synthetase 1 (mitochondrial)

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04745 FAR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04748 FARS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22167 Far2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fars2 NCBI NCBI:10667