Afap1 - actin filament associated protein 1 Gene

Also Known as Afap; mKIAA3018; 2600003E23Rik; 9630044L16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70292

Summary

Predicted to enable SH2 domain binding activity and SH3 domain binding activity. Predicted to be involved in regulation of signal transduction. Predicted to be located in actin filament and focal adhesion. Predicted to be active in cytosol. Is expressed in cerebral cortex subventricular zone and cerebral cortex ventricular layer. Human ortholog(s) of this gene implicated in open-angle glaucoma. Orthologous to human AFAP1 (actin filament associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Afap1 Products (4)

mRNA Protein Name
NM_001403419.1 NP_001390348.1 actin filament-associated protein 1 isoform 1
NM_001403420.1 NP_001390349.1 actin filament-associated protein 1 isoform 3
NM_001403421.1 NP_001390350.1 actin filament-associated protein 1 isoform 4
NM_027373.3 NP_081649.1 actin filament-associated protein 1 isoform 2
Protein Preferred Names Protein Names

actin filament-associated protein 1

  • 110 kDa actin filament-associated protein

  • AFAP-110

Orthologs Information

Species Symbol Source ID
Homo sapiens Afap1 NCBI NCBI:60312