Afap1 - actin filament associated protein 1 Gene

Mus musculus

Also known as Afap; mKIAA3018; 2600003E23Rik; 9630044L16Rik

Gene ID: 70292 | Gene type: protein coding

About Afap1

Summary

Predicted to enable SH2 domain binding activity and SH3 domain binding activity. Predicted to be involved in regulation of signal transduction. Predicted to be located in actin filament and focal adhesion. Predicted to be active in cytosol. Is expressed in cerebral cortex subventricular zone and cerebral cortex ventricular layer. Human ortholog(s) of this gene implicated in open-angle glaucoma. Orthologous to human AFAP1 (actin filament associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Afap1 Products(4)

mRNA	Protein	Name
NM_001403419.1	NP_001390348.1	actin filament-associated protein 1 isoform 1
NM_001403420.1	NP_001390349.1	actin filament-associated protein 1 isoform 3
NM_001403421.1	NP_001390350.1	actin filament-associated protein 1 isoform 4
NM_027373.3	NP_081649.1	actin filament-associated protein 1 isoform 2

Protein Preferred Names

Protein Names

actin filament-associated protein 1

110 kDa actin filament-associated protein

AFAP-110

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00425	AFAP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS00426	AFAP1L2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Afap1	NCBI	NCBI:60312

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