Polr3b - polymerase (RNA) III (DNA directed) polypeptide B Gene

Also Known as C128; RPC2; 2700078H01Rik; A330032P03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70428

Summary

Predicted to enable several functions, including DNA binding activity; metal ion binding activity; and ribonucleoside binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in positive regulation of innate immune response and positive regulation of interferon-beta production. Predicted to act upstream of or within defense response to virus and innate immune response. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism. Orthologous to human POLR3B (RNA polymerase III subunit B). [provided by Alliance of Genome Resources, Apr 2022]

Polr3b Products (1)

mRNA Protein Name
NM_027423.2 NP_081699.1 DNA-directed RNA polymerase III subunit RPC2
Protein Preferred Names Protein Names

DNA-directed RNA polymerase III subunit RPC2

  • DNA-directed RNA polymerase III 127.6 kDa polypeptide

  • DNA-directed RNA polymerase III subunit B

  • RNA polymerase III subunit C2

  • RNA polymerase III subunit RPC2 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10856 POLR3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Polr3b NCBI NCBI:55703