Polr3b - polymerase (RNA) III (DNA directed) polypeptide B Gene

Mus musculus

Also known as C128; RPC2; 2700078H01Rik; A330032P03Rik

Gene ID: 70428 | Gene type: protein coding

About Polr3b

Summary

Predicted to enable several functions, including DNA binding activity; metal ion binding activity; and ribonucleoside binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in positive regulation of innate immune response and positive regulation of interferon-beta production. Predicted to act upstream of or within defense response to virus and innate immune response. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism. Orthologous to human POLR3B (RNA polymerase III subunit B). [provided by Alliance of Genome Resources, Apr 2022]

Polr3b Products(1)

mRNA	Protein	Name
NM_027423.2	NP_081699.1	DNA-directed RNA polymerase III subunit RPC2

Protein Preferred Names

Protein Names

DNA-directed RNA polymerase III subunit RPC2

DNA-directed RNA polymerase III 127.6 kDa polypeptide	DNA-directed RNA polymerase III subunit B
RNA polymerase III subunit C2	RNA polymerase III subunit RPC2 homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10856	POLR3B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Polr3b	NCBI	NCBI:55703

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