Ipo5 - importin 5 Gene

Also Known as IMB3; imp5; Kpnb3; Ranbp5; 1110011C18Rik; 5730478E03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70572

Summary

Enables nuclear import signal receptor activity. Involved in NLS-bearing protein import into nucleus; cellular response to amino acid stimulus; and positive regulation of protein import into nucleus. Located in cytoplasm and nucleus. Is expressed in germ cell of testis; gonad; ovary; spermatid; and testis. Orthologous to human IPO5 (importin 5). [provided by Alliance of Genome Resources, Apr 2022]

Ipo5 Products (2)

mRNA Protein Name
NM_001360602.1 NP_001347531.1 importin-5 isoform 2
NM_023579.4 NP_076068.1 importin-5 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables nuclear import signal receptor activity IDA
IDA: Inferred from direct assay
17143267 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11809816 MGI
Biological Process GO Annotation Evidence References Source
involved in NLS-bearing protein import into nucleus IDA
IDA: Inferred from direct assay
17143267 MGI
involved in cellular response to amino acid stimulus IDA
IDA: Inferred from direct assay
22730302 MGI
involved in positive regulation of protein import into nucleus IMP
IMP: Inferred from mutant phenotype
22730302 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
22730302 MGI
located in nucleus IDA
IDA: Inferred from direct assay
17143267 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

importin-5

  • RAN binding protein 5

  • importin beta 3

  • importin subunit beta-3

  • karyopherin (importin) beta 3

  • karyopherin beta-3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06869 IPO5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ipo5 NCBI NCBI:3843