Prdm5 - PR domain containing 5 Gene

Also Known as PFM2; 4432417F03Rik; 6530401I24Rik; E130112L17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70779

Summary

Predicted to enable DNA-binding transcription factor binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Predicted to be located in nuclear body and nucleolus. Is expressed in several structures, including brain; early embryo; and genitourinary system. Human ortholog(s) of this gene implicated in brittle cornea syndrome 2. Orthologous to human PRDM5 (PR/SET domain 5). [provided by Alliance of Genome Resources, Apr 2022]

Prdm5 Products (2)

mRNA Protein Name
NM_027547.2 NP_081823.2 PR domain zinc finger protein 5 isoform 1
NM_029549.1 NP_083825.1 PR domain zinc finger protein 5 isoform 2
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PR domain zinc finger protein 5

  • PR domain-containing protein 5

Orthologs Information

Species Symbol Source ID
Homo sapiens Prdm5 NCBI NCBI:11107