Pdss2 - prenyl (solanesyl) diphosphate synthase, subunit 2 Gene

Also Known as kd; Gm60; Plmp; mDLP1; 5430420P03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71365

Summary

Enables protein heterodimerization activity. Contributes to trans-hexaprenyltranstransferase activity and trans-octaprenyltranstransferase activity. Involved in cerebellum development; isoprenoid biosynthetic process; and ubiquinone biosynthetic process. Acts upstream of or within regulation of body fluid levels. Located in mitochondrion. Part of transferase complex. Is expressed in endocrine gland; genitourinary system; nervous system; skin; and stomach. Used to study coenzyme Q10 deficiency disease. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 3. Orthologous to human PDSS2 (decaprenyl diphosphate synthase subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Pdss2 Products (2)

mRNA Protein Name
NM_001168289.1 NP_001161761.1 all trans-polyprenyl-diphosphate synthase PDSS2 isoform 2
NM_027772.2 NP_082048.2 all trans-polyprenyl-diphosphate synthase PDSS2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity IDA
IDA: Inferred from direct assay
16262699 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16262699 MGI
enables protein heterodimerization activity IDA
IDA: Inferred from direct assay
16262699 MGI
Biological Process GO Annotation Evidence References Source
involved in cerebellum development IMP
IMP: Inferred from mutant phenotype
21871565 MGI
involved in isoprenoid biosynthetic process IDA
IDA: Inferred from direct assay
16262699 MGI
acts upstream of or within regulation of body fluid levels IMP
IMP: Inferred from mutant phenotype
5098070 MGI
involved in ubiquinone biosynthetic process IDA
IDA: Inferred from direct assay
16262699 MGI
Cellular Component GO Annotation Evidence References Source
part of heterotetrameric polyprenyl diphosphate synthase complex IDA
IDA: Inferred from direct assay
16262699 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

all trans-polyprenyl-diphosphate synthase PDSS2

decaprenyl-diphosphate synthase subunit 2

  • all-trans-decaprenyl-diphosphate synthase subunit 2

  • decaprenyl pyrophosphate synthase subunit 2

  • decaprenyl pyrophosphate synthetase subunit 2

  • prenyltransferase-like mitochondrial protein

  • solanesyl-diphosphate synthase subunit 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10294 PDSS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22715 Pdss2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29229 Pdss2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdss2 NCBI NCBI:57107