Suds3 - suppressor of defective silencing 3 homolog (S. cerevisiae) Gene

Also Known as mSds3; 2400003N08Rik; 2410008L21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71954

Summary

Enables histone deacetylase binding activity and identical protein binding activity. Acts upstream of or within blastocyst hatching and negative regulation of DNA-templated transcription. Part of Sin3-type complex. Is expressed in several structures, including 1-cell stage conceptus; 2-cell stage conceptus; 4-8 cell stage conceptus; gonad; and morula-stage conceptus. Orthologous to human SUDS3 (SIN3A corepressor complex component SDS3). [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in colon adult (RPKM 43.8), ovary adult (RPKM 42.1) and 28 other tissues.

Suds3 Products (2)

mRNA Protein Name
NM_001122666.2 NP_001116138.1 sin3 histone deacetylase corepressor complex component SDS3 isoform b
NM_178622.5 NP_848737.3 sin3 histone deacetylase corepressor complex component SDS3 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables histone deacetylase binding IDA
IDA: Inferred from direct assay
11909966 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
11909966 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11909966 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within blastocyst hatching IMP
IMP: Inferred from mutant phenotype
27869233 MGI
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
15489224 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11909966 MGI
Cellular Component GO Annotation Evidence References Source
part of Sin3-type complex IDA
IDA: Inferred from direct assay
11909966 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Suds3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Suds3 Q8BR65 Sin3a Mus musculus Q60520
CoIP
11909966
Intra
Suds3 Q8BR65 Suds3 Mus musculus Q8BR65
Anti Tag CoIP
11909966
Intra
Suds3 Q8BR65 Sin3b Mus musculus Q62141
Pull Down
11909966
Intra
Suds3 Q8BR65 Suds3 Mus musculus Q8BR65
Y2H
11909966
Intra
Suds3 Q8BR65 Suds3 Mus musculus Q8BR65
Pull Down
11909966
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14048 SUSD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22840 Susd3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29355 Susd3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Suds3 NCBI NCBI:64426