ZBED2 - zinc finger BED-type containing 2 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79413

About ZBED2

Cytogenetic location: 3q13.13 Genomic coordinates (GRCh38): 3:111,592,900-111,595,346 (from NCBI)

This gene has 1 transcript (splice variant) and 64 orthologues. Biased expression in thyroid (RPKM 46.0), lung (RPKM 7.6) and 2 other tissues.

Summary

Enables transcription cis-regulatory region binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of keratinocyte differentiation. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

ZBED2 Products (1)

mRNA Protein Name
NM_024508.5 NP_078784.2 zinc finger BED domain-containing protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
32385160 GOA
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
32385160 GOA
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
32385160 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
32385160 GOA
involved in positive regulation of keratinocyte differentiation IMP
IMP: Inferred from mutant phenotype
31552090 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZBED2 Protein Structure

zf-BED

zf-BED: BED zinc finger (55 - 107)

  • 0
  • 100
  • 200
  • 218 a.a.
Protein Preferred Names Protein Names

zinc finger BED domain-containing protein 2

  • zinc finger, BED domain containing 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15955 ZBED2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown