2. Gene
  3. TTLL7 - tubulin tyrosine ligase like 7 Gene

TTLL7 - tubulin tyrosine ligase like 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 79739 | Gene type: protein coding

About TTLL7

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:83,865,024-83,999,132 (from NCBI)

This gene has 14 transcripts (splice variants), 195 orthologues and 12 paralogues. Broad expression in brain (RPKM 22.0), prostate (RPKM 4.2) and 14 other tissues.

Summary

Enables alpha-tubulin binding activity; beta-tubulin binding activity; and tubulin-glutamic acid ligase activity. Involved in protein polyglutamylation. Predicted to be located in 9+0 non-motile cilium and ciliary basal body. Predicted to be active in cilium. [provided by Alliance of Genome Resources, Apr 2022]

TTLL7 Products(3)

mRNA Protein Name
NM_001350214.2 NP_001337143.1 tubulin polyglutamylase TTLL7 isoform 1
NM_001350215.2 NP_001337144.1 tubulin polyglutamylase TTLL7 isoform 2
NM_024686.6 NP_078962.4 tubulin polyglutamylase TTLL7 isoform 1

TTLL7 Protein Structure

TTL

TTL: Tubulin-tyrosine ligase family (90 - 379)

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  • 887 a.a.
Protein Preferred Names Protein Names

tubulin polyglutamylase TTLL7

testis development protein NYD-SP30

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15234 TTLL7 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TTLL7 VGNC VGNC:36495
Felis catus TTLL7 VGNC VGNC:66689
Canis familiaris TTLL7 VGNC VGNC:47978
Macaca mulatta TTLL7 VGNC VGNC:79591
Mus musculus TTLL7 MGD MGI:1918142
Rattus norvegicus TTLL7 RGD RGD:1566117